CELL BIOLOGY BBI1205
TOPICS and REQUIREMENTS
Lectures
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Week |
Topic |
Remarks |
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1 |
Organization of the prokaryotic and eukaryotic cells. Origin of the eukaryotic cell |
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2 |
The structure and function of plasma membrane. Membrane transport |
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3 |
Electrical properties of membranes. Glycocalyx. Cell surface antigens, receptors. Cell adhesion |
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4 |
The cytosol and the cytoskeleton |
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5 |
Cellular motility |
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6 |
Types and functions of the endoplasmic reticulum |
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7 |
The Golgi apparatus. The endosomal-lysosomal compartment |
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8 |
Endocytosis, exocytosis, secretion |
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9 |
The structure and function of peroxisomes, mitochondria, and chloroplasts |
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10 |
Nuclear structure and function |
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11 |
Chromatin and chromosomes |
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12 |
The cell cycle. Mitosis |
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13 |
Meiosis |
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14 |
The differentiation, ageing and death of cells |
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Practical course
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Week |
Topic |
Remarks |
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1-2 |
General laboratory, occupational safety and fire regulations. Laboratory schedule. Operation of the light microscope. |
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3-4 |
The organization of fungal cells. Observation of yeast model organisms in light microscope |
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5-6 |
The organization of plant and animal cells. Staining of plant cells for light microscopic observation. Examination of human blood in light microscope |
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7-8 |
The types of cell division. Examination of chromosomes in plant cells |
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9-10 |
The structure of electron microscopes. Methods for preparation of EM specimens. Recognition and characterization of organelles in EM images. Basics of fluorescence microscopy. Luminescent labeling of cellular structures |
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11-12 |
Cell culture basics. Visit in the Agricultural and Molecular Research Institute (fluorescence microscope, cell culture laboratory) |
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13-14 |
Closing exercise. Evaluation of the semester's work. |
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Requirements:
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Participation in classes: |
Attending the lectures is recommended. Participation in the practical course is mandatory. |
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Inspections during the semester: |
Regular mid-term tests in practical course |
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Credit assigned to the subject: |
4 |
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Method of determining the grade: |
Accomplishment of the practical course is a precondition to taking an oral exam. Evaluation of the performance: 0-49 %: fail 50-59 %: pass 60-79 % satisfactory 80-89 %: good 90-100 %: excellent |
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Recommended readings: |
Students receive the ppt presentations of the lectures (in pdf format) at the beginning of the course. Alberts, Hopkin, Johnson et.al.,: Essential cell biology. 5th edition. W.W. Norton & Company, 2019. ISBN-13 978-0393680379 |
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Recommended homepages: |
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